产品货号:
Z35454
中文名称:
P glycoprotein/ABCB1抗体
英文名称:
Anti-P glycoprotein/ABCB1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-P glycoprotein/ABCB1 Antibody |
指标别名 | ABCB1;CD243;GP170;MDR1;Multidrug resistance protein 1;P glycoprotein;P glycoprotein 1;P-gp |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | ABCB1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human P Glycoprotein |
实际分子量 | 130~180KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | P-GP,also called ABCB1 or PGY1,is a glycoprotein that in humans is encoded by the ABCB1 gene.It is mapped to 7q21.12.P-GP is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.It is an important protein of the cell membrane that pumps many foreign substances out of cells.More formally,it is an ATP-dependent drug efflux pump with broad substrate specificity.P-GP is an ATP-dependent drug efflux pump forxenobiotic compounds with broad substrate specificity.It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs.This protein also functions as a transporter in the blood–brain barrier. |
Uniprot ID | P08183 |
基因名全称 | Multidrug resistance protein 1 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 |
相关搜索:P glycoprotein/ABCB1抗体,P glycoprotein抗体,ABCB1单抗,Anti-P glycoprotein/ABCB1 Antibody